What GI docs really care about is when patterns change. So if your stool is suddenly much looser than it used to be—and it does not get better within a few days—it is time to talk to your doctor. The National Institute of Diabetes and Digestive and Kidney Diseases suggests that adults who have had diarrhea for more than two days seek medical help; if you have a fever or notice blood or pus in your stool, you probably ought to phone your physician even sooner.

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